RAF Typhoon FGR4s have joined forces with France's air force in a coordinated attack against an underground arms cache in Syrian territory employed by the Islamic State group (IS), according to the UK's MoD.
The site, located using surveillance, was believed to be housing weapons and explosive materials, the statement said, and was located in mountainous terrain just north of the ancient city of Palmyra in Syria's central region.
"Our aircraft employed precision-guided Paveway IV munitions to target a series of access tunnels down to the facility... early reports suggest the objective was successfully hit," the MoD said.
There was no sign of any harm to civilians in the strike conducted Saturday night and each participating jet returned safely, the ministry further stated.
The Typhoon fighters were assisted by a Voyager refuelling tanker.
The Islamic State group - alternatively referred to as Daesh - enforced jihadist rule over significant areas in Syria and Iraq until 2019.
"This action underscores our UK leadership, and resolve to operate in unison with our partners, to stamp out any resurgence of the terrorist group and their harmful and extremist ideologies in the area," UK Defence Secretary the Defence Secretary stated.
RAF aircraft have carried out surveillance missions over Syrian airspace to "prevent any attempted resurgence" of Islamic State subsequent to its routing at the Baghuz confrontation in 2019, the MoD reported.
"I want to thank every member of our armed forces participating in this strike for their expertise and their bravery," the Defence Secretary added. "They were among a great many British troops on duty over the festive period. This action, to take out terrorist threats who endanger our safety, highlights how our armed forces are always on standby, all year round, protecting the UK domestically and strong abroad."
Last December, the American forces executed what it termed a "large-scale strike" against Daesh sites in Syria, after an ambush resulted in the deaths of two US servicemembers and a local interpreter in Palmyra.
The UN says Daesh still has an estimated 5,000 to 7,000 militants in Syria and Iraq.